I dont think Mozilla alone can kill microsoft. The main part in the Computer supply chain is the hardware. And every chip maker and assembler has tied up with microsoft. Other day I was looking for a vanilla laptop and there was none (Dell gives you with red hat but you are on your own). If a company comes with all harware support for linux systems that could kill MS. Personal Computers days are gone, now days have started of task oriented, networked compters and microsoft is lagging in it.
The only thing which could kill microsoft is microsoft itself and their future products. (Vista is just a begining).
I have stopped using XP for past 6 months as ubuntu gives me all that I want plus with very good usability and performance that you can never think of using MS.